The contestant is shown two prizes, both of which are locked inside a giant safe. The three-digit price of the smaller item represents the combination of the safe. The digits in the price of the smaller prize are shown on each of three dials; each digit appears only once in the price. The contestant must set the dials to the price of the three-digit prize to open the safe and win both prizes.
- Early in the game's history, the game often had a full six possible combinations for the three-digit item's price. Since the mid-1980s, however, the three-digit price has virtually always ended in zero, making the game an either-or proposition of choosing the first two numbers if the contestant is aware of this fact. At the very least, if the combination contains a zero, there are only four possible combinations, since zero cannot be the first digit in a price.
- From the game's introduction, the game's signature tune was "The Pink Panther Theme", composed by Henry Mancini. Due to the licensing costs, it has since been replaced by two different sets of stock music, in both cases being carried over from syndicated nighttime versions. The first of these stock cues was first used on the 1985-86 nighttime version with Tom Kennedy before carrying over to the daytime show on February 11, 1992 (#8302D). The game's current think cue was originally used on 1994's The New Price Is Right with Doug Davidson before its daytime debut on April 27, 1995 (#9564D). (The Australian and German versions were still using the Pink Panther theme by this time, though.)
- In addition to the initial use of the daytime show's current think cue, the 1994 syndicated version also staged the game differently. The safe only contained the main prize while the smaller prize whose price was used for the combination of the safe was placed outside the safe and talked about after the safe was locked.
- Starting in Season 34, the door that contains the Safe Crackers game is already open as the winning One Bid contestant comes on stage. Drew Carey also removes the correct price marker from the envelope, regardless if the contestant won or lost the game while Bob Barker only revealed the marker if the contestant lost. Originally, if the game was lost, one of the models dialed the correct digits and opened the safe.
- On the $1,000,000 Spectacular on February 29, 2008 (#025SP, aired out of order on April 11), Safe Crackers was featured as the Million Dollar Game. After the main prize (a car) was won in addition to the 3-digit prize, the contestant could risk the prizes won to play for $1 million. The setup had 5 dials in the price of the car, with the possibility of repeating numbers. Contestant Domus Go opted not to play for the million and kept the prizes he already won.
- On October 13, 2015 (#7242K, aired out of order on October 16, originally rescheduled to air on October 14), during Price's Big Money Week, a cash prize of $10,000 was offered as the larger prize and it was won.
- On December 7, 2016 (#7713K), Rachel didn't open the safe then it did open afterwards by offered a Alaska Tour Cruise and the glasses and won.
- On February 17, 2017 (#7815K), the losing horns were played.
- Safe Crackers always offers 2 prizes. The first one is the combination to the safe and the 2nd one is either a car or a prize that's less or more than $10,000.
- The one prize that is less than $1,000 cannot have any repeating numbers, but the grand prize can have some repeating numbers.
- The most number of times this game was played in any season was 49.
- The safe's locking mechanism is a rod inserted into a clip on the door. A backstage stagehand removes the rod if the safe is cracked.
- Mathematically, there are 6 possible combinations for the three digits. However, one of the numbers is always a 0, and so since the first number cannot be a 0, and the 0 is always used for the last number, there are only 2 of those combinations that are likely to be used.
- Safe Crackers was one of seven pricing games seen on the third taping session of Season 36, which was seen on October 17, 2007 (#4043K, aired out of order on November 13), October 25, 2007 (#4054K, aired out of order on January 3, 2008), October 29, 2007 (#4061K, aired out of order on December 13), November 6, 2007 (#4072K, aired out of order on October 17), November 15, 2007 (#4084K, aired out of order on November 7), and November 23, 2007 (#4095K, aired out of order on October 26).
- On the UK Joe Pasquale version, Safecrackers used a real safe and only offered the three-digit prize.
- On Hãy chọn giá đúng, the game was titled "Két Sắt" (Safe). The game was the same as the one used in US, except that each of the dials had a different set of digits, making it more difficult.
Safe Crackers for a Pair of Benelli Motorcycles and 2 Raleigh Bicycles (December 14, 1977, #2603D)Edit
Safe Crackers for a Dynafoil Watercraft and a Moped (October 25, 1979, #3444D)Edit
A Safe Crackers Technical Win (October 6, 1980, #3811D)Edit
A Safe Crackers Christmas Eve Win (December 24, 1981, #4324D)Edit
Safe Crackers for a Ford Escort L 2-Door and a Besco Truckaway Utility Trailer (January 25, 1982, #4371D)Edit
An Appliance Blooper in Safe Crackers (January 6, 1983, #4744D)Edit
Safe Crackers for a Mazda B2000 (February 3, 1984, #5185D)Edit
A Jeep Win from the 14th Season Premiere (September 9, 1985, #5791D)Edit
Safe Crackers for a Plymouth Voyager (September 9, 1985, #N 0011)Edit
A Car Win from the Season 15 Premiere (September 8, 1986, #6171D)Edit
Safe Crackers as a Play Along Game (January 14, 1987, #6333D)Edit
Safe Crackers for a Bookcase Wall Unit and a Pair of Harris Lamps (February 6, 1987, #6365D)Edit
Safe Crackers for a Baseball Fantasy Camp Trip (September 26, 1994, #0011N)Edit
Safe Crackers for a Trip to Scotland (October 12, 1994)Edit
Safe Crackers for a Regal Jet Boat and a Pair of Water Ski equipment from Jet Ryder (October 18, 1994)Edit
Safe Crackers for a Hooker Home Theatre Wall Unit w/RCA Home Theatre 52" Projection TV and a Collection of Walt Disney Home Videos (December 13, 1994, #9392D)Edit
Safe Crackers for a Geo Tracker Convertible (September 9, 1997, #0432K)Edit
Safe Crackers Without the Safe Background (May 22, 2004, #018SP)Edit
Last Safe Crackers Car Playing with Bob Barker (November 7, 2006, #3752K)Edit
Final Playing with Bob Barker (June 6, 2007, #4023K)Edit
First Safe Crackers Winner With Drew Carey (November 6, 2007, #4072K, aired out of order on October 17 as the first playing with Drew)Edit
Safe Crackers as a Million Dollar Game (February 29, 2008, #025SP, aired out of order on April 11)Edit
Safe Crackers for a Water Ventures Aquatic Trike and a Supply of Rocky Mountain Sunblock (April 17, 2008, #4294K)Edit
A Safe Crackers Mishap (October 24, 2008, #4475K)Edit
Safe Crackers for a Dodge Avenger SXT (November 4, 2008, #4492K, aired out of order on October 28)Edit
Safe Crackers for a Hyundai Sonata GLS (March 29, 2010, #5101K)Edit
Safe Crackers for a Toyota Camry LE (October 29, 2010, #5285K)Edit
Safe Crackers for $10,000 (October 13, 2015, #7242K, aired out of order on October 16, originally rescheduled to air on October 14)Edit
From October 5, 2017 (#8034K)Edit
Safe Crackers for an Online Shopping Spree (October 19, 2018, #8455K)Edit
Safe Crackers for a $15,220 Trip to Denmark (December 6, 2018, #8524K, aired out of order on June 25, 2019)Edit
Daniel's Sea-Doo Watercraft and Bonus Deluxe Bahamas Vacation Win (September 25, 2019, #8823K, aired out of order on December 6, originally rescheduled to air on September 26, area in the Bahamas was not hit by Hurricane Dorian.)Edit
Safe Crackers With Cedric Yarbrough, Jean-Luc Bilodeau, and Lucas Neff from Carol's Second Act (January 9, 2020, #8974K)Edit
Safe Crackers played for a Car (Season 15 Premiere, September 8, 1986) (#6171D)
Safe Crackers played for a Car and a WILD contestant
A Safe Crackers Primetime Playing
A Safe Crackers Win plus $500 bonus